Large-scale mitogenomic analysis of the phylogeography of the Late Pleistocene cave bear
2019
Аутори
Gretzinger, J.Molak, M.
Reiter, E.
Pfrengle, S.
Urban, C.
Neukamm, J.
Blant, M.
Conard, N.J.
Cupillard, Christophe
Dimitrijević, Vesna
Drucker, Dorothee G.
Hofman-Kamińska, E.
Kowalczyk, R.
Krajcarz, M.T.
Krajcarz, M.
Münzel, S.C.
Peresani, M.
Romandini, M.
Rufí, I.
Soler, J.
Terlato, G.
Krause, J.
Bocherens, H.
Schuenemann, V.J.
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The cave bear (Ursus spelaeus) is one of the Late Pleistocene megafauna species that faced extinction at the end of the last ice age. Although it is represented by one of the largest fossil records in Europe and has been subject to several interdisciplinary studies including palaeogenetic research, its fate remains highly controversial. Here, we used a combination of hybridisation capture and next generation sequencing to reconstruct 59 new complete cave bear mitochondrial genomes (mtDNA) from 14 sites in Western, Central and Eastern Europe. In a Bayesian phylogenetic analysis, we compared them to 64 published cave bear mtDNA sequences to reconstruct the population dynamics and phylogeography during the Late Pleistocene. We found five major mitochondrial DNA lineages resulting in a noticeably more complex biogeography of the European lineages during the last 50,000 years than previously assumed. Furthermore, our calculated effective female population sizes suggest a drastic cave bear p...opulation decline starting around 40,000 years ago at the onset of the Aurignacian, coinciding with the spread of anatomically modern humans in Europe. Thus, our study supports a potential significant human role in the general extinction and local extirpation of the European cave bear and illuminates the fate of this megafauna species.
Извор:
Scientific Reports, 2019, 9, 1Издавач:
- Nature Publishing Group
DOI: 10.1038/s41598-019-47073-z
ISSN: 2045-2322
PubMed: 31417104
WoS: 000480679700001
Scopus: 2-s2.0-85070942427
Институција/група
Arheologija / ArchaeologyTY - JOUR AU - Gretzinger, J. AU - Molak, M. AU - Reiter, E. AU - Pfrengle, S. AU - Urban, C. AU - Neukamm, J. AU - Blant, M. AU - Conard, N.J. AU - Cupillard, Christophe AU - Dimitrijević, Vesna AU - Drucker, Dorothee G. AU - Hofman-Kamińska, E. AU - Kowalczyk, R. AU - Krajcarz, M.T. AU - Krajcarz, M. AU - Münzel, S.C. AU - Peresani, M. AU - Romandini, M. AU - Rufí, I. AU - Soler, J. AU - Terlato, G. AU - Krause, J. AU - Bocherens, H. AU - Schuenemann, V.J. PY - 2019 UR - http://reff.f.bg.ac.rs/handle/123456789/2909 AB - The cave bear (Ursus spelaeus) is one of the Late Pleistocene megafauna species that faced extinction at the end of the last ice age. Although it is represented by one of the largest fossil records in Europe and has been subject to several interdisciplinary studies including palaeogenetic research, its fate remains highly controversial. Here, we used a combination of hybridisation capture and next generation sequencing to reconstruct 59 new complete cave bear mitochondrial genomes (mtDNA) from 14 sites in Western, Central and Eastern Europe. In a Bayesian phylogenetic analysis, we compared them to 64 published cave bear mtDNA sequences to reconstruct the population dynamics and phylogeography during the Late Pleistocene. We found five major mitochondrial DNA lineages resulting in a noticeably more complex biogeography of the European lineages during the last 50,000 years than previously assumed. Furthermore, our calculated effective female population sizes suggest a drastic cave bear population decline starting around 40,000 years ago at the onset of the Aurignacian, coinciding with the spread of anatomically modern humans in Europe. Thus, our study supports a potential significant human role in the general extinction and local extirpation of the European cave bear and illuminates the fate of this megafauna species. PB - Nature Publishing Group T2 - Scientific Reports T1 - Large-scale mitogenomic analysis of the phylogeography of the Late Pleistocene cave bear IS - 1 VL - 9 DO - 10.1038/s41598-019-47073-z ER -
@article{ author = "Gretzinger, J. and Molak, M. and Reiter, E. and Pfrengle, S. and Urban, C. and Neukamm, J. and Blant, M. and Conard, N.J. and Cupillard, Christophe and Dimitrijević, Vesna and Drucker, Dorothee G. and Hofman-Kamińska, E. and Kowalczyk, R. and Krajcarz, M.T. and Krajcarz, M. and Münzel, S.C. and Peresani, M. and Romandini, M. and Rufí, I. and Soler, J. and Terlato, G. and Krause, J. and Bocherens, H. and Schuenemann, V.J.", year = "2019", abstract = "The cave bear (Ursus spelaeus) is one of the Late Pleistocene megafauna species that faced extinction at the end of the last ice age. Although it is represented by one of the largest fossil records in Europe and has been subject to several interdisciplinary studies including palaeogenetic research, its fate remains highly controversial. Here, we used a combination of hybridisation capture and next generation sequencing to reconstruct 59 new complete cave bear mitochondrial genomes (mtDNA) from 14 sites in Western, Central and Eastern Europe. In a Bayesian phylogenetic analysis, we compared them to 64 published cave bear mtDNA sequences to reconstruct the population dynamics and phylogeography during the Late Pleistocene. We found five major mitochondrial DNA lineages resulting in a noticeably more complex biogeography of the European lineages during the last 50,000 years than previously assumed. Furthermore, our calculated effective female population sizes suggest a drastic cave bear population decline starting around 40,000 years ago at the onset of the Aurignacian, coinciding with the spread of anatomically modern humans in Europe. Thus, our study supports a potential significant human role in the general extinction and local extirpation of the European cave bear and illuminates the fate of this megafauna species.", publisher = "Nature Publishing Group", journal = "Scientific Reports", title = "Large-scale mitogenomic analysis of the phylogeography of the Late Pleistocene cave bear", number = "1", volume = "9", doi = "10.1038/s41598-019-47073-z" }
Gretzinger, J., Molak, M., Reiter, E., Pfrengle, S., Urban, C., Neukamm, J., Blant, M., Conard, N.J., Cupillard, C., Dimitrijević, V., Drucker, D. G., Hofman-Kamińska, E., Kowalczyk, R., Krajcarz, M.T., Krajcarz, M., Münzel, S.C., Peresani, M., Romandini, M., Rufí, I., Soler, J., Terlato, G., Krause, J., Bocherens, H.,& Schuenemann, V.J.. (2019). Large-scale mitogenomic analysis of the phylogeography of the Late Pleistocene cave bear. in Scientific Reports Nature Publishing Group., 9(1). https://doi.org/10.1038/s41598-019-47073-z
Gretzinger J, Molak M, Reiter E, Pfrengle S, Urban C, Neukamm J, Blant M, Conard N, Cupillard C, Dimitrijević V, Drucker DG, Hofman-Kamińska E, Kowalczyk R, Krajcarz M, Krajcarz M, Münzel S, Peresani M, Romandini M, Rufí I, Soler J, Terlato G, Krause J, Bocherens H, Schuenemann V. Large-scale mitogenomic analysis of the phylogeography of the Late Pleistocene cave bear. in Scientific Reports. 2019;9(1). doi:10.1038/s41598-019-47073-z .
Gretzinger, J., Molak, M., Reiter, E., Pfrengle, S., Urban, C., Neukamm, J., Blant, M., Conard, N.J., Cupillard, Christophe, Dimitrijević, Vesna, Drucker, Dorothee G., Hofman-Kamińska, E., Kowalczyk, R., Krajcarz, M.T., Krajcarz, M., Münzel, S.C., Peresani, M., Romandini, M., Rufí, I., Soler, J., Terlato, G., Krause, J., Bocherens, H., Schuenemann, V.J., "Large-scale mitogenomic analysis of the phylogeography of the Late Pleistocene cave bear" in Scientific Reports, 9, no. 1 (2019), https://doi.org/10.1038/s41598-019-47073-z . .