Neuromodulation of short-term associative memory: A comparison between constant anodal tDCS, oscillatory tDCS, and tACS
Апстракт
Transcranial electric stimulation (tES) techniques are promising tools for neuromodulation of memory functions. However, previous findings on effectiveness of tES are inconsistent and there have been very few studies directly contrasting different types of stimulation. Here we comparatively assess the effectiveness of constant anodal tDCS (1.5mA), oscillatory tDCS (otDCS, 1.5mA ± 0.5mA) at individual theta frequency (ITF)(4-8Hz) and tACS at ITF (0±1mA) over left posterior parietal cortex for the enhancement of short-term associative memory (STAM). In the sham-controlled cross-over experiment participants (N=40) underwent four conditions (tDCS/otDCS/tACS/sham) in counterbalanced order while they performed parallel forms of the STAM task. The STAM task consisted of digit-color association sequences in which single-digits (0 9) were presented sequentially on the colored cards (green/blue/yellow/red/pink/gray) and participants were instructed to remember digit-color associations. The seque...nce length varied between 3 (low-demand) to 5 stimuli (high-demand). At the end of each sequence, the participants were presented with one of the previously seen colored cards and they needed to recall the digit that was presented on a given card. Planed contrasts have shown that relative to sham, tDCS improved STAM in both low- [F(1,39)=7.39, p=.010, ηp2=.16] and high-demand sequences [F(1,39)=4.71, p=.036, ηp2=.11], while tACS [F(1,39)=4.42, p=.042, ηp2=.10] and otDCS [F(1,39)=4.79, p=.035, ηp2=.11] exclusively improved memory performance in high-demand sequences. The results suggest that different stimulation protocols affect different processes – namely, tDCS effects seem to be mediated by facilitation of lower-level attentional processes while the effects of oscillatory protocols tend to affect memory processes in a more focal manner.
Кључне речи:
associative memory / transcranial direct current stimulation (tdcs) / transcranial alternating current stimulation (tacs) / transcranial oscillatory current stimulation (otdcs)Извор:
Cognitive Neuroscience Society CNS - Annual meeting (23-26 April, San Francisco, USA), 2022Финансирање / пројекти:
- Science Fund of the Republic of Serbia - project MEMORYST (grant no. 6058808)
- Ministry of Education, Science, and Technological development of the Republic of Serbia (University of Belgrade, Faculty of Philosophy - grant no. 451-03-68/2022-14/200163)
- Ministry of Education, Science, and Technological development of the Republic of Serbia (University of Belgrade, Institute for Medical Research - grant no. 451-03- 68/2022-14/200015)
Институција/група
Psihologija / PsychologyTY - CONF AU - Živanović, Marko AU - Bjekić, Jovana AU - Filipović, Saša R. PY - 2022 UR - http://reff.f.bg.ac.rs/handle/123456789/4883 AB - Transcranial electric stimulation (tES) techniques are promising tools for neuromodulation of memory functions. However, previous findings on effectiveness of tES are inconsistent and there have been very few studies directly contrasting different types of stimulation. Here we comparatively assess the effectiveness of constant anodal tDCS (1.5mA), oscillatory tDCS (otDCS, 1.5mA ± 0.5mA) at individual theta frequency (ITF)(4-8Hz) and tACS at ITF (0±1mA) over left posterior parietal cortex for the enhancement of short-term associative memory (STAM). In the sham-controlled cross-over experiment participants (N=40) underwent four conditions (tDCS/otDCS/tACS/sham) in counterbalanced order while they performed parallel forms of the STAM task. The STAM task consisted of digit-color association sequences in which single-digits (0 9) were presented sequentially on the colored cards (green/blue/yellow/red/pink/gray) and participants were instructed to remember digit-color associations. The sequence length varied between 3 (low-demand) to 5 stimuli (high-demand). At the end of each sequence, the participants were presented with one of the previously seen colored cards and they needed to recall the digit that was presented on a given card. Planed contrasts have shown that relative to sham, tDCS improved STAM in both low- [F(1,39)=7.39, p=.010, ηp2=.16] and high-demand sequences [F(1,39)=4.71, p=.036, ηp2=.11], while tACS [F(1,39)=4.42, p=.042, ηp2=.10] and otDCS [F(1,39)=4.79, p=.035, ηp2=.11] exclusively improved memory performance in high-demand sequences. The results suggest that different stimulation protocols affect different processes – namely, tDCS effects seem to be mediated by facilitation of lower-level attentional processes while the effects of oscillatory protocols tend to affect memory processes in a more focal manner. C3 - Cognitive Neuroscience Society CNS - Annual meeting (23-26 April, San Francisco, USA) T1 - Neuromodulation of short-term associative memory: A comparison between constant anodal tDCS, oscillatory tDCS, and tACS UR - https://hdl.handle.net/21.15107/rcub_reff_4883 ER -
@conference{ author = "Živanović, Marko and Bjekić, Jovana and Filipović, Saša R.", year = "2022", abstract = "Transcranial electric stimulation (tES) techniques are promising tools for neuromodulation of memory functions. However, previous findings on effectiveness of tES are inconsistent and there have been very few studies directly contrasting different types of stimulation. Here we comparatively assess the effectiveness of constant anodal tDCS (1.5mA), oscillatory tDCS (otDCS, 1.5mA ± 0.5mA) at individual theta frequency (ITF)(4-8Hz) and tACS at ITF (0±1mA) over left posterior parietal cortex for the enhancement of short-term associative memory (STAM). In the sham-controlled cross-over experiment participants (N=40) underwent four conditions (tDCS/otDCS/tACS/sham) in counterbalanced order while they performed parallel forms of the STAM task. The STAM task consisted of digit-color association sequences in which single-digits (0 9) were presented sequentially on the colored cards (green/blue/yellow/red/pink/gray) and participants were instructed to remember digit-color associations. The sequence length varied between 3 (low-demand) to 5 stimuli (high-demand). At the end of each sequence, the participants were presented with one of the previously seen colored cards and they needed to recall the digit that was presented on a given card. Planed contrasts have shown that relative to sham, tDCS improved STAM in both low- [F(1,39)=7.39, p=.010, ηp2=.16] and high-demand sequences [F(1,39)=4.71, p=.036, ηp2=.11], while tACS [F(1,39)=4.42, p=.042, ηp2=.10] and otDCS [F(1,39)=4.79, p=.035, ηp2=.11] exclusively improved memory performance in high-demand sequences. The results suggest that different stimulation protocols affect different processes – namely, tDCS effects seem to be mediated by facilitation of lower-level attentional processes while the effects of oscillatory protocols tend to affect memory processes in a more focal manner.", journal = "Cognitive Neuroscience Society CNS - Annual meeting (23-26 April, San Francisco, USA)", title = "Neuromodulation of short-term associative memory: A comparison between constant anodal tDCS, oscillatory tDCS, and tACS", url = "https://hdl.handle.net/21.15107/rcub_reff_4883" }
Živanović, M., Bjekić, J.,& Filipović, S. R.. (2022). Neuromodulation of short-term associative memory: A comparison between constant anodal tDCS, oscillatory tDCS, and tACS. in Cognitive Neuroscience Society CNS - Annual meeting (23-26 April, San Francisco, USA). https://hdl.handle.net/21.15107/rcub_reff_4883
Živanović M, Bjekić J, Filipović SR. Neuromodulation of short-term associative memory: A comparison between constant anodal tDCS, oscillatory tDCS, and tACS. in Cognitive Neuroscience Society CNS - Annual meeting (23-26 April, San Francisco, USA). 2022;. https://hdl.handle.net/21.15107/rcub_reff_4883 .
Živanović, Marko, Bjekić, Jovana, Filipović, Saša R., "Neuromodulation of short-term associative memory: A comparison between constant anodal tDCS, oscillatory tDCS, and tACS" in Cognitive Neuroscience Society CNS - Annual meeting (23-26 April, San Francisco, USA) (2022), https://hdl.handle.net/21.15107/rcub_reff_4883 .