Personalized frequency modulated transcranial electrical stimulation for associative memory enhancement
Autori
Bjekić, JovanaŽivanović, Marko
Paunović, Dunja
Vulić, Katarina
Konstantinović, Uroš
Filipović, Saša R.
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Associative memory (AM) is the ability to remember the relationship between previously
unrelated items. AM is significantly affected by normal aging and neurodegenerative conditions,
thus there is a growing interest in applying non-invasive brain stimulation (NIBS) techniques for
AM enhancement. A growing body of studies identifies posterior parietal cortex (PPC) as the most
promising cortical target for both transcranial magnetic stimulation (TMS) and transcranial electrical stimulation (tES) to modulate a cortico-hippocampal network that underlines AM. In that sense, theta frequency oscillatory tES protocols, targeted towards the hallmark oscillatory activity within the cortico-hippocampal network, are increasingly coming to prominence. To increase precision and effectiveness, the need for EEG guided individualization of the tES protocols is proposed. Here, we present the study protocol in which two types of personalized oscillatory tES–transcranial alternating current stimulatio...n (tACS) and oscillatory transcranial direct current stimulation (otDCS), both frequency-modulated to the individual theta-band frequency (ITF), are compared to the nonoscillatory transcranial direct current stimulation (tDCS) and to the sham stimulation. The study has cross-over design with four tES conditions (tACS, otDCS, tDCS, sham), and the comprehensive set of neurophysiological (resting state EEG and AM-evoked EEG) and behavioral outcomes, including AM tasks (short-term associative memory, face–word, face–object, object-location), as well as measures of other cognitive functions (cognitive control, verbal fluency, and working memory).
Ključne reči:
associative memory / transcranial direct current stimulation (tDCS) / transcranial alternating current stimulation (tACS) / transcranial oscillatory current stimulation (otDCS) / personalized brain stimulation / individual theta-band frequency / EEG / cognitive assessmentIzvor:
Brain Sciences, 2022, 12, 4, 472-Izdavač:
- Basel : MDPI
Finansiranje / projekti:
- Science Fund of the Republic of Serbia - project MEMORYST (grant no. 6058808)
- Ministry of Education, Science and Technological Development, Republic of Serbia (University of Belgrade, Faculty of Philosophy - grant no. 451-03-9/2021-14/200163, 451-03-68/2022-14/200163)
- Ministry of Education, Science and Technological Development, Republic of Serbia (University of Belgrade, Institute for Medical Research - grant no. 451-03-9/2021-14/200015, 451-03-68/2022-14/200015)
DOI: 10.3390/brainsci12040472
ISSN: 2076-3425
WoS: 00078599950000
Scopus: 2-s2.0-85128349228
Institucija/grupa
Psihologija / PsychologyTY - JOUR AU - Bjekić, Jovana AU - Živanović, Marko AU - Paunović, Dunja AU - Vulić, Katarina AU - Konstantinović, Uroš AU - Filipović, Saša R. PY - 2022 UR - http://reff.f.bg.ac.rs/handle/123456789/4004 AB - Associative memory (AM) is the ability to remember the relationship between previously unrelated items. AM is significantly affected by normal aging and neurodegenerative conditions, thus there is a growing interest in applying non-invasive brain stimulation (NIBS) techniques for AM enhancement. A growing body of studies identifies posterior parietal cortex (PPC) as the most promising cortical target for both transcranial magnetic stimulation (TMS) and transcranial electrical stimulation (tES) to modulate a cortico-hippocampal network that underlines AM. In that sense, theta frequency oscillatory tES protocols, targeted towards the hallmark oscillatory activity within the cortico-hippocampal network, are increasingly coming to prominence. To increase precision and effectiveness, the need for EEG guided individualization of the tES protocols is proposed. Here, we present the study protocol in which two types of personalized oscillatory tES–transcranial alternating current stimulation (tACS) and oscillatory transcranial direct current stimulation (otDCS), both frequency-modulated to the individual theta-band frequency (ITF), are compared to the nonoscillatory transcranial direct current stimulation (tDCS) and to the sham stimulation. The study has cross-over design with four tES conditions (tACS, otDCS, tDCS, sham), and the comprehensive set of neurophysiological (resting state EEG and AM-evoked EEG) and behavioral outcomes, including AM tasks (short-term associative memory, face–word, face–object, object-location), as well as measures of other cognitive functions (cognitive control, verbal fluency, and working memory). PB - Basel : MDPI T2 - Brain Sciences T1 - Personalized frequency modulated transcranial electrical stimulation for associative memory enhancement IS - 4 SP - 472 VL - 12 DO - 10.3390/brainsci12040472 ER -
@article{ author = "Bjekić, Jovana and Živanović, Marko and Paunović, Dunja and Vulić, Katarina and Konstantinović, Uroš and Filipović, Saša R.", year = "2022", abstract = "Associative memory (AM) is the ability to remember the relationship between previously unrelated items. AM is significantly affected by normal aging and neurodegenerative conditions, thus there is a growing interest in applying non-invasive brain stimulation (NIBS) techniques for AM enhancement. A growing body of studies identifies posterior parietal cortex (PPC) as the most promising cortical target for both transcranial magnetic stimulation (TMS) and transcranial electrical stimulation (tES) to modulate a cortico-hippocampal network that underlines AM. In that sense, theta frequency oscillatory tES protocols, targeted towards the hallmark oscillatory activity within the cortico-hippocampal network, are increasingly coming to prominence. To increase precision and effectiveness, the need for EEG guided individualization of the tES protocols is proposed. Here, we present the study protocol in which two types of personalized oscillatory tES–transcranial alternating current stimulation (tACS) and oscillatory transcranial direct current stimulation (otDCS), both frequency-modulated to the individual theta-band frequency (ITF), are compared to the nonoscillatory transcranial direct current stimulation (tDCS) and to the sham stimulation. The study has cross-over design with four tES conditions (tACS, otDCS, tDCS, sham), and the comprehensive set of neurophysiological (resting state EEG and AM-evoked EEG) and behavioral outcomes, including AM tasks (short-term associative memory, face–word, face–object, object-location), as well as measures of other cognitive functions (cognitive control, verbal fluency, and working memory).", publisher = "Basel : MDPI", journal = "Brain Sciences", title = "Personalized frequency modulated transcranial electrical stimulation for associative memory enhancement", number = "4", pages = "472", volume = "12", doi = "10.3390/brainsci12040472" }
Bjekić, J., Živanović, M., Paunović, D., Vulić, K., Konstantinović, U.,& Filipović, S. R.. (2022). Personalized frequency modulated transcranial electrical stimulation for associative memory enhancement. in Brain Sciences Basel : MDPI., 12(4), 472. https://doi.org/10.3390/brainsci12040472
Bjekić J, Živanović M, Paunović D, Vulić K, Konstantinović U, Filipović SR. Personalized frequency modulated transcranial electrical stimulation for associative memory enhancement. in Brain Sciences. 2022;12(4):472. doi:10.3390/brainsci12040472 .
Bjekić, Jovana, Živanović, Marko, Paunović, Dunja, Vulić, Katarina, Konstantinović, Uroš, Filipović, Saša R., "Personalized frequency modulated transcranial electrical stimulation for associative memory enhancement" in Brain Sciences, 12, no. 4 (2022):472, https://doi.org/10.3390/brainsci12040472 . .
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