A direct comparison of tDCS, theta tACS, and theta‑oscillatory tDCS effects on short-term associative memory
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Objectives:
To comparatively assess the online effects of constant anodal tDCS, oscillatory tDCS, and tACS over the left posterior parietal cortex on the short-term associative memory.
Content:
Transcranial electric stimulation (tES) techniques are promising tools for the neuromodulation of memory functions. Here, we comparatively assess the online effects of three tES protocols over the left posterior parietal cortex on the short-term associative memory (AM): oscillatory tDCS (otDCS, 1.5 mA ± 0.5 mA), tACS (0 ± 1 mA), both delivered at personalized theta frequency (4–8 Hz) and constant anodal tDCS (1.5 mA). Forty participants took part in a sham-controlled cross-over experiment where they received different tES protocols in separate sessions (tDCS/otDCS/tACS/sham) while performing parallel forms of the short-term AM task. In AM task, single digits were successively presented on the cards of different colors (digit-color associations). The length of sequences varied between three (l...ow-demand) to five stimuli (high-demand). The participant’s task was to remember digit-color associations presented in each sequence. At the end of each sequence, participants were shown one of the previously seen color cards, and they needed to recall the digit that was presented on a given card. Results showed that
participants outperformed sham in all three real tES conditions. Despite comparable effectiveness, the effects of tES protocols varied depending on the task demand, with tDCS being more beneficial
when the memory demand was low, while theta-modulated tACS and otDCS predominantly promoted short-term AM when the memory load was high. The results indicate that tDCS, otDCS, and tACS, due to their different modes of action, potentially affect different memory processes.
Keywords:
transcranial direct current stimulation (tdcs) / transcranial alternating current stimulation (tacs) / individual theta frequency / associative memorySource:
Clinical Neurophysiology, 2023, 150, e122-e122Funding / projects:
- Horizon Europe - project “Twinning for excellence in non-invasive brain stimulation in Western Balkans” (project no 101059369)
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200163 (University of Belgrade, Faculty of Philosophy) (RS-MESTD-inst-2020-200163)
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200015 (University of Belgrade, Institute for Medical Research) (RS-MESTD-inst-2020-200015)
Note:
- Abstracts of the 18th European Congress of Clinical Neurophysiology (ECCN), Marseille, France, May 9–12, 2023
Institution/Community
Psihologija / PsychologyTY - CONF AU - Živanović, Marko AU - Bjekić, Jovana AU - Konstantinović, Uroš AU - Filipović, Saša R. PY - 2023 UR - http://reff.f.bg.ac.rs/handle/123456789/4856 AB - Objectives: To comparatively assess the online effects of constant anodal tDCS, oscillatory tDCS, and tACS over the left posterior parietal cortex on the short-term associative memory. Content: Transcranial electric stimulation (tES) techniques are promising tools for the neuromodulation of memory functions. Here, we comparatively assess the online effects of three tES protocols over the left posterior parietal cortex on the short-term associative memory (AM): oscillatory tDCS (otDCS, 1.5 mA ± 0.5 mA), tACS (0 ± 1 mA), both delivered at personalized theta frequency (4–8 Hz) and constant anodal tDCS (1.5 mA). Forty participants took part in a sham-controlled cross-over experiment where they received different tES protocols in separate sessions (tDCS/otDCS/tACS/sham) while performing parallel forms of the short-term AM task. In AM task, single digits were successively presented on the cards of different colors (digit-color associations). The length of sequences varied between three (low-demand) to five stimuli (high-demand). The participant’s task was to remember digit-color associations presented in each sequence. At the end of each sequence, participants were shown one of the previously seen color cards, and they needed to recall the digit that was presented on a given card. Results showed that participants outperformed sham in all three real tES conditions. Despite comparable effectiveness, the effects of tES protocols varied depending on the task demand, with tDCS being more beneficial when the memory demand was low, while theta-modulated tACS and otDCS predominantly promoted short-term AM when the memory load was high. The results indicate that tDCS, otDCS, and tACS, due to their different modes of action, potentially affect different memory processes. C3 - Clinical Neurophysiology T1 - A direct comparison of tDCS, theta tACS, and theta‑oscillatory tDCS effects on short-term associative memory EP - e122 SP - e122 VL - 150 DO - 10.1016/j.clinph.2023.03.156 ER -
@conference{ author = "Živanović, Marko and Bjekić, Jovana and Konstantinović, Uroš and Filipović, Saša R.", year = "2023", abstract = "Objectives: To comparatively assess the online effects of constant anodal tDCS, oscillatory tDCS, and tACS over the left posterior parietal cortex on the short-term associative memory. Content: Transcranial electric stimulation (tES) techniques are promising tools for the neuromodulation of memory functions. Here, we comparatively assess the online effects of three tES protocols over the left posterior parietal cortex on the short-term associative memory (AM): oscillatory tDCS (otDCS, 1.5 mA ± 0.5 mA), tACS (0 ± 1 mA), both delivered at personalized theta frequency (4–8 Hz) and constant anodal tDCS (1.5 mA). Forty participants took part in a sham-controlled cross-over experiment where they received different tES protocols in separate sessions (tDCS/otDCS/tACS/sham) while performing parallel forms of the short-term AM task. In AM task, single digits were successively presented on the cards of different colors (digit-color associations). The length of sequences varied between three (low-demand) to five stimuli (high-demand). The participant’s task was to remember digit-color associations presented in each sequence. At the end of each sequence, participants were shown one of the previously seen color cards, and they needed to recall the digit that was presented on a given card. Results showed that participants outperformed sham in all three real tES conditions. Despite comparable effectiveness, the effects of tES protocols varied depending on the task demand, with tDCS being more beneficial when the memory demand was low, while theta-modulated tACS and otDCS predominantly promoted short-term AM when the memory load was high. The results indicate that tDCS, otDCS, and tACS, due to their different modes of action, potentially affect different memory processes.", journal = "Clinical Neurophysiology", title = "A direct comparison of tDCS, theta tACS, and theta‑oscillatory tDCS effects on short-term associative memory", pages = "e122-e122", volume = "150", doi = "10.1016/j.clinph.2023.03.156" }
Živanović, M., Bjekić, J., Konstantinović, U.,& Filipović, S. R.. (2023). A direct comparison of tDCS, theta tACS, and theta‑oscillatory tDCS effects on short-term associative memory. in Clinical Neurophysiology, 150, e122-e122. https://doi.org/10.1016/j.clinph.2023.03.156
Živanović M, Bjekić J, Konstantinović U, Filipović SR. A direct comparison of tDCS, theta tACS, and theta‑oscillatory tDCS effects on short-term associative memory. in Clinical Neurophysiology. 2023;150:e122-e122. doi:10.1016/j.clinph.2023.03.156 .
Živanović, Marko, Bjekić, Jovana, Konstantinović, Uroš, Filipović, Saša R., "A direct comparison of tDCS, theta tACS, and theta‑oscillatory tDCS effects on short-term associative memory" in Clinical Neurophysiology, 150 (2023):e122-e122, https://doi.org/10.1016/j.clinph.2023.03.156 . .