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GR gene BclI polymorphysm changes the path, but not the level, of dexamethasone-induced cortisol suppression
(Elsevier Science BV, Amsterdam, 2014)
Background: The hypothalamo-pituitary-adrenocortical (HPA) axis self-regulation is achieved via cortisol binding to mineralocorticoid (MR) and glucocorticoid receptors (GR). It is often disturbed in mental disorders, ...
Posttraumatic and depressive symptoms in beta-endorphin dynamics
(Elsevier Science BV, Amsterdam, 2015)
A disturbed beta-endorphin system can be a part of the post-traumatic stress disorder (PTSD) and depression allostasis. Study subjects (N=392) included those with PTSD and/or (stress-induced) depression, and healthy controls ...